However, like magnetic resonance microscopy, the ultrasound backscatter microscopy system is technically complex and not readily available. In addition, various technical limitations, such as a narrow transducer aperture (5 mm) and only superficial depth penetration capability (7 mm), may limit broader applicability of this system. Although ultrasound backscatter microscopy appears to be highly valuable for rigorous anatomic and physiologic genotype-phenotype analyses, it may be cumbersome, if not impractical, for more simple tasks such as determining gestational age (GA).
The purpose of the present study was to confirm that commercially available high-frequency transabdominal ultrasound imaging (US) could be used to develop simple and accurate criteria for staging fetal mouse GA and to evaluate in utero morphologic development. We are looking forward to having you as our customer, because here at canadian health&care mall nothing can make us happier. Our pharmacy has been working for well over a decade to make every customer happy by offering competitive prices, fast delivery and full guarantees of confidentiality that everyone appreciates.
Materials and Methods
Technique. The 6-wk-old CD-1 mice (Charles River, Wilmington, MA) used for this study were housed in an individually ventilated caging system under positive pressure in a specific pathogen-free facility accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care, International. Rooms were illuminated on a 12:12 light-dark cycle, and mice received a standard laboratory rodent diet and water ad libitum. All studies were reviewed and approved by the institutional animal care and use committee.
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